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The nearest rail services are located at Grand Island, 11 miles north, and at Hastings, 14 miles south of Doniphan.

Amtrak provides Hastings with rail passenger service east to Chicago and west to Denver and San Francisco/Oakland.


U.S. Highway 281 (north-south) serves Doniphan, and Interstate 80 (east/west) is 3 miles north. There are no local load restrictions. Four-lane U.S. Highway 281 is 45 miles east, Interstate 29 is 150 miles east, and Interstate 70 is 170 miles south, and Interstate 90 is 191 miles north of Doniphan.


Commercial air service is available at the Central Nebraska Regional Airport near Grand Island, 18 miles (20 minutes) north of Doniphan. Passenger, air express, and air freight services are provided. The conveniently located airport offers regular flights to Las Vegas, Utah, Mesa, Arizona, and Dallas, Texas.